Chicago Site-Specific Scientific Initiatives

As a MWCCS study participant, you may be eligible to participate in a number of substudies. Study staff will confirm your study eligibility.


HIV serostatus has been shown to increase risk for osteoporosis, loss of bone density, and sarcopenia. The purpose of this study is to evaluate your bone mineral density. The test is non-invasive and radiation-free. The Ultrascan 650 is a rapid portable device that sends an ultrasound wave across your forearm (⅓ distal radius). This procedure takes 10-15 minutes.


The gold standard bone density test DXA can determine whether or not a patient has osteoporosis (disease that breaks down bone tissue, making them fragile and more likely to break) or osteopenia (low bone density). It measures your bone mineral density (BMD) from two areas of the body: (1) lumbar spine, which is the vertebrae in the lower part of the spine and (2) the hip. 


WatchPAT is a portable device worn on your wrist during sleep. It uses proprietary PAT (Peripheral Arterial Tonometry) technology to assess sleep metrics and quantify sleep apnea. 

Joint Pain

The PEG questionnaire evaluates pain intensity in various joints: hip, knee, and spine and how pain affects your enjoyment of life and general activity.

Climate Anxiety

You will be given a questionnaire to assess your experience with the effect of climate change and global warming on your physical and mental health.